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Please use this identifier to cite or link to this item: http://hdl.handle.net/10271/3205

Title: Hepatic relaxation times from postmortem MR imaging of adult humans
Other Titles: ヒト成人死後MRIの肝臓緩和時間
Authors: Shiotani, Seiji
塩谷, 清司
Keywords: liver
in vivo
low body temperature
T1 and T2 values
postmortem magnetic resonance imaging
Issue Date: 2016
Publisher: Japanese Society for Magnetic Resonance in Medicine
Abstract: Purpose: To measure T1 and T2 values of hepatic postmortem magnetic resonance (PMMR) imaging. Materials and Methods: We performed hepatic PMMR imaging of 22 deceased adults (16 men, 6 women; mean age, 56.3 years) whose deaths were for reasons other than liver injury or disease at a mean of 27.7 hours after death. Before imaging, the bodies were kept in cold storage at 4°C (mean rectal temperature, 17.6°C). We measured T1 and T2 values in the liver at two sites (the anterior segment of the right lobe and the lateral segment of the left lobe). We also investigated the influence of the body temperature and postmortem interval on T1 and T2 values. Results: In the anterior segment of the right lobe and the lateral segment of the left lobe, T1 values of PMMR imaging were 524 ± 112 ms and 472 ± 104 ms (mean ± standard deviation), respectively; while T2 values were 42 ± 6 ms and 43 ± 8 ms, respectively. T1 and T2 values did not differ significantly between the two sites (P ≧ 0.05). Regarding temperature, the T2 values of hepatic PMMR imaging were linearly correlated with the body temperature, but the T1 values were not. The T1 and T2 values of the two sites in the liver did not correlate with the postmortem interval. Conclusion: Reduction in body temperature after death is considered to induce T1 and T2 value changes in the liver on PMMR imaging.
Description: 浜松医科大学学位論文 医博論第530号(平成28年9月16日)
URI: http://hdl.handle.net/10271/3205
DOI: info:doi/10.2463/mrms.mp.2015-0086
NII paper ID: http://ci.nii.ac.jp/naid/130005117120
PubMed ID: info:pmid/26701693
Ichushi ID: 2017136574
Academic Degrees and number: 13802乙第530号
Degree-granting date: 2016-09-16
Degree name: 博士(医学)
Degree-granting institutions: 浜松医科大学
Appears in Collections:2010 博士(論文)

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